P41 Characterization and Management of Elderly and Very Elderly Patients with Non–Small Cell Lung Cancer
نویسندگان
چکیده
منابع مشابه
Second-line therapy in elderly patients with advanced nonsmall cell lung cancer.
There is no dedicated study on second-line treatment for elderly patients with advanced nonsmall cell lung cancer (NSCLC). We report the results on second-line erlotinib therapy from our previously published phase III study comparing single-agent therapy with platinum-based doublet (carboplatin plus paclitaxel) therapy in 451 elderly patients. Erlotinib was given to patients exhibiting disease ...
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The peak incidence of lung cancer in the UK is between 75 and 80 years of age, reported at 751 per 100 000 in men over 75 years, with over half of 500 000 patients diagnosed annually worldwide being over the age of 70. 3 It is therefore an enormous health burden on our ageing populations and will, in the medium term, pose a significant challenge to health services worldwide as the age distribut...
متن کاملTherapeutic management of ALK+ nonsmall cell lung cancer patients.
With therapeutic approaches based on oncogene addiction offering significant anticancer benefit, the identification of anaplastic lymphoma kinase (ALK) rearrangements is a key aspect of the management of lung cancers. The EML4-ALK gene fusion is detected in 4-8% of all lung cancers, predominantly in light smokers or nonsmokers. Crizotinib, the first agent to be approved in this indication, is a...
متن کاملElderly patients with advanced non-small-cell lung cancer.
Advanced non-small cell lung cancer (NSCLC) in elderly patients is an increasingly common problem which the practitioner of oncology must face. There is no consensus on the cut-off age for defining the elderly. However, 70 years may be the most appropriate because the incidence of age-related changes starts to increase after this boundary. Important concerns in evaluating the treatment of elder...
متن کاملIs surgery indicated for elderly patients with early stage nonsmall cell lung cancer, in the era of stereotactic body radiotherapy?
BACKGROUND The aim of this article is to assess the influence of comorbidities among elderly patients (at least 70 year old) undergoing surgery for early stage nonsmall cell lung cancer (NSCLC) and to explore the tolerability and efficacy of surgery in relation to stereotactic body radiotherapy (SBRT) in this patient population. METHODS A review of the literature on the prevalence of comorbid...
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ژورنال
عنوان ژورنال: Journal of Thoracic Oncology
سال: 2018
ISSN: 1556-0864
DOI: 10.1016/j.jtho.2018.07.080